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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ITGA4 All Species: 19.04
Human Site: S1029 Identified Species: 34.91
UniProt: P13612 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P13612 NP_000876.3 1032 114872 S1029 W S Y I N S K S N D D _ _ _ _
Chimpanzee Pan troglodytes XP_525977 1032 114817 S1029 W S Y I N S K S N D D _ _ _ _
Rhesus Macaque Macaca mulatta XP_001100929 1032 114958 S1029 W S Y I N S K S N D D _ _ _ _
Dog Lupus familis XP_545551 1165 128321 S1161 W S Y V N S K S N D D D _ _ _
Cat Felis silvestris
Mouse Mus musculus Q00651 1039 115677 S1036 W S Y V N S K S N D D _ _ _ _
Rat Rattus norvegicus Q63258 1135 124176 K1090 R E D R Q Q F K E E K T G T I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515892 940 104353
Chicken Gallus gallus P26008 1034 114370 T1031 P H E N G E G T S E A _ _ _ _
Frog Xenopus laevis Q91687 1032 115197 D1027 S W N Y L N K D E K E V K _ _
Zebra Danio Brachydanio rerio XP_002663459 1018 113210 E1015 W D Y V P K H E S V S _ _ _ _
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24247 1146 127955 L1136 M N E E K P F L A P S K N T H
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34446 1226 135921 D1206 Q P N A Q Y A D S Q S R Y T S
Sea Urchin Strong. purpuratus XP_794080 1226 134761 R1217 M Q A P G A Q R G P M G Q L R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 97 75.1 N.A. 84.1 25.8 N.A. 65.5 26.2 54.4 47.6 N.A. 24 N.A. 22.1 24.7
Protein Similarity: 100 99.9 98.4 81.7 N.A. 91.8 44.4 N.A. 77.5 46.6 74.1 65.3 N.A. 43.4 N.A. 41.3 42.9
P-Site Identity: 100 100 100 83.3 N.A. 90.9 0 N.A. 0 0 7.6 18.1 N.A. 0 N.A. 0 0
P-Site Similarity: 100 100 100 91.6 N.A. 100 20 N.A. 0 27.2 23 36.3 N.A. 6.6 N.A. 13.3 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 8 0 8 8 0 8 0 8 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 8 0 0 0 0 16 0 39 39 8 0 0 0 % D
% Glu: 0 8 16 8 0 8 0 8 16 16 8 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 16 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 16 0 8 0 8 0 0 8 8 0 0 % G
% His: 0 8 0 0 0 0 8 0 0 0 0 0 0 0 8 % H
% Ile: 0 0 0 24 0 0 0 0 0 0 0 0 0 0 8 % I
% Lys: 0 0 0 0 8 8 47 8 0 8 8 8 8 0 0 % K
% Leu: 0 0 0 0 8 0 0 8 0 0 0 0 0 8 0 % L
% Met: 16 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % M
% Asn: 0 8 16 8 39 8 0 0 39 0 0 0 8 0 0 % N
% Pro: 8 8 0 8 8 8 0 0 0 16 0 0 0 0 0 % P
% Gln: 8 8 0 0 16 8 8 0 0 8 0 0 8 0 0 % Q
% Arg: 8 0 0 8 0 0 0 8 0 0 0 8 0 0 8 % R
% Ser: 8 39 0 0 0 39 0 39 24 0 24 0 0 0 8 % S
% Thr: 0 0 0 0 0 0 0 8 0 0 0 8 0 24 0 % T
% Val: 0 0 0 24 0 0 0 0 0 8 0 8 0 0 0 % V
% Trp: 47 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 47 8 0 8 0 0 0 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 47 54 62 62 % _